Anti-Mouse CD71 In Vivo Antibody (OX-26) - Low Endotoxin [ICH1197]
Catalogue Number: ICH1197-ICB
| Manufacturer: | IchorBio |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 mg, 25 mg, 5 mg, 50 mg |
| Host name: | Mouse |
| Clone: | OX-26 |
| Isotype: | IgG2a |
| Immunogen: | |
| Application: | FC, IHC |
Description
Description: CD71 is a transferrin receptor on the cell surface that mediates the uptake of transferrin-iron complexes, thereby mediating cellular proliferation. CD71 is a homodimeric glycoprotein containing 760 amino acids and it binds to diferric transferrin. Binding by diferric transfferin causes CD71 to be internalized, and diferric iron is subsequently released. CD71 is highly expressed on malignant cells, as iron uptake is necessary for aberrant cell proliferation.
Additional Text
Purification
Protein A/G Purified
Antibody Clonality
Monoclonal
Application Notes
Each investigator should determine their own optimal working dilution for specific applications.
Concentration
≥ 2 mg/ml
SUPPORT
outstanding technical support
PRODUCT
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DELIVERY
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