Utomilumab Biosimilar - Research Grade [ICH5014]

Catalogue Number: ICH5014-ICB

Manufacturer:IchorBio
Type:Recombinant Monoclonal
Alias:4-1BB ligand receptor, T-cell antigen 4-1BB, Tnfrsf9, Ila, Ly63, CD137
Shipping Condition:Blue Ice
Unit(s): 10 mg, 20 mg, 5 mg, 50 mg, 1 mg, 100 mg
Host name:
Clone:
Isotype: IgG2, lambda
Immunogen:
Application: FA

Description

Description: RUO Utomilumab is a fully-human IgG2 agonist mAb that selectively binds human 4-1BB/CD137, resulting in NF-κB activation and downstream cytokine production in cell lines and primary lymphocytes. Utomilumab can induce human leukocyte proliferation and has demonstrated significant antitumor activity as a single agent in human peripheral blood lymphocyte (PBL) SCID xenograft tumor models.

Additional Text

Gene ID

3604

Gene Name

TNFRSF9

Concentration

5 mg/ml

Uniprot ID

Q07011

Purification

Protein A/G Purified

Antibody Clonality

Recombinant Monoclonal

Application Notes

This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Storage Note

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Price
£1,118.00


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