Theralizumab Biosimilar - Research Grade

Catalogue Number: ICH5023-ICB

Manufacturer:IchorBio
Type:Recombinant Monoclonal
Alias:TGN1412, CD28-SuperMAB, TAB08
Shipping Condition:Blue Ice
Unit(s): 5 mg, 10 mg, 20 mg, 50 mg, 1 mg, 100 mg
Host name:
Clone:
Isotype: IgG4
Immunogen:
Application: FA

Description

Description: Theralizumab GN1412 is a humanised monoclonal antibody that not only binds to, but is a strong agonist for, the CD28 receptor of the immune system's T cells. CD28 is the co-receptor for the T cell receptor; It binds to receptors on the interacting partner in the reaction through one of its ligands (B7 family). It was withdrawn from development after inducing severe inflammatory reactions as well as chronic organ failure in the first-in-human study by PAREXEL in London in March 2006.

Additional Text

Gene ID

940

Concentration

5 mg/ml

Gene Name

CD28

Uniprot ID

P10747

Purification

Protein A/G Purified

Antibody Clonality

Recombinant Monoclonal

Application Notes

This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Storage Note

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Price
£701.00


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