Anti-RAS (G12V Mutant) from Rabbit (HL169) - unconj.

Catalogue Number: IHC-184012-DIA

Manufacturer:Dianova
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone: HL169
Isotype: IgG
Immunogen: Synthetic peptide corresponding to human RAS (G12V Mutant).
Application: IHC-P, IHC

Description

Description: Antibody clone HL10 has been validated to specifically detect RAS G12V Mutant RAS protein in paraffin-embedded tumor tissue by immunohiostochemistry. KRAS is a preeminent oncoprotein as it is mutated in more than 85% of RAS-altered cancers. Despite the common G12D mutation, G12V plays an important role to prevent Ras inactivation in several tumors.

Additional Text

Gene Name

KRAS

Concentration

1 mg/ml

Uniprot ID

P01116

Gene ID

3845

Purification

Protein G purified

Antibody Clonality

Monoclonal