Cynomolgus IL-1 Beta/IL-1F2 Protein (IL1-CE10B)
Catalogue Number: IL1-CE10B-KAT
IL1-CE10B Image
IL1-CE10B Image
IL1-CE10B Image
IL1-CE10B Image
Human IL-1 RII, hFc Tag captured on CM5 Chip via Protein A can bind Cynomolgus IL-1 Beta, His Tag with an affinity constant of 1.40 nM as determined in SPR assay (Biacore T200).
IL1-CE10B Image
The purity of Cynomolgus IL-1 Beta is greater than 95% as determined by SEC-HPLC.
IL1-CE10B Image
Cynomolgus IL-1 Beta on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 18.33 kDa same as Bis-Tris PAGE result. |
| Physical state: | Lyophilized |
| Type: | Cytokines |
| Alias: | Interleukin-1 beta; IL-1 beta; IL1F2; IL1B; IL-1BETA; IL1F2; IL-1β; IL-1 beta; IL-1B ;Interleukin-1 β; IL-1 β; IL-1β; IL-1 β |
| Host Cell: | E.coli |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
| Application: | WB |
Description
Description: Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1 signaling activates innate immune cells including antigen presenting cells, and drives polarization of CD4 T cells towards T helper type (Th) 1 and Th17 cells.
Additional Text
Protein Tag
HIS Tag
Short Description
Recombinant Cynomolgus IL-1 Beta/IL-1F2 Protein is expressed from E.coli with His tag at the C-Terminus.It contains Ala117-Ser268.
UniProt ID
A0A2K5VDC7
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biological Activity
The affinity constant of 0.92 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Endotoxin
Less than 1 EU per µg by the LAL method.
IL1-CE10B Datasheet
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