Biotinylated Human IL-18 Protein (Primary Amine Labeling) (IL1-HE018B)

Catalogue Number: IL1-HE018B-KAT

Manufacturer:Kactus
Shelf Life:12 months
Molecular Weight:The protein has a predicted MW of 18.2 kDa same as Bis-Tris PAGE result.
Physical state:Lyophilized
Type:Protein - Conjugated
Alias:IL-18; IL18; IGIF; IL-1F4; IL-1 gamma; IL1F4; IL-1g; Interleukin 1; IL-1γ; IL-1 γ
Host Cell:E.coli
Shipping Condition:RT
Unit(s): 100 ug, 500 ug
Application: ELISA, WB

Description

Description: Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naive T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation.

Additional Text

Gene Name

IL18

Gene ID

3606

Uniprot ID

Q14116

Protein Tag

Untagged

Storage Note

-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Short Description

Recombinant Biotinylated Human IL-18 Protein (Primary Amine Labeling) is expressed from E.coli without tag.; It contains Tyr37-Asp193.

Biological Activity

Immobilized Human IL-18BP, hFc Tag at 5Oeg/ml (100Oel/well) on the plate. Dose response curve for Biotinylated Human IL-18, No Tag with the EC50 of 26.0ng/ml determined by ELISA. See testing image for detail.

Endotoxin

Less than 1 EU per µg by the LAL method.

Price
£413.00


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