Human IL-1 Beta/IL-1F2 Protein (IL1-HE40B)

Catalogue Number: IL1-HE40B-KAT

Manufacturer:	Kactus
Shelf Life:	12 months
Molecular Weight:	The protein has a predicted MW of 20.1 kDa same as Bis-Tris PAGE result.
Physical state:	Lyophilized
Type:	Other Recombinant Protein
Alias:	Interleukin-1 beta; IL-1 beta; IL1F2; IL1B; IL-1BETA; IL1F2; IL-1β; IL-1 beta; IL-1B ;Interleukin-1 β; IL-1 β; IL-1β; IL-1 β
Host Cell:	E.coli
Shipping Condition:	RT
Unit(s):	100 ug, 500 ug
Application:	ELISA, WB

Overview
Datasheets

Description

Description: Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1 signaling activates innate immune cells including antigen presenting cells, and drives polarization of CD4 T cells towards T helper type (Th) 1 and Th17 cells.

Additional Text

Gene Name

IL1B

Gene ID

3553

Uniprot ID

P01584

Protein Tag

HIS-AviTag™

Short Description

Recombinant Human IL-1 Beta/IL-1F2 Protein is expressed from E.coil with His tag and Avi tag at the C-Terminus.It contains Ala117-Ser269.

Storage Note

-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Biological Activity

Immobilized Human IL-1 Beta, His Tag at 5Oeg/ml (100Oel/Well) on the plate. Dose response curve for Human IL-1R2, hFc Tag with the EC50 of 0.44Oeg/ml determined by ELISA. The affinity constant of 0.88 nM as determined in SPR assay (Biacore T200). See testing image for detail.

Endotoxin

Less than 1 EU per µg by the LAL method.

IL1-HE40B Datasheet

IL1-HE40B MSDS

Price

£212.00

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