Human IL-1F10/IL-38 Protein (ILF-HY138)

Catalogue Number: ILF-HY138-KAT

Manufacturer:Kactus
Shelf Life:12 months
Molecular Weight:The protein has a predicted MW of 18.07 kDa. Due to glycosylation, the protein migrates to 20-23 kDa based on Bis-Tris PAGE result.
Physical state:Lyophilized
Type:Interleukins
Alias:FIL1 theta; IL-1HY2; IL-1 theta; IL38
Host Cell:Yeast
Shipping Condition:RT
Unit(s): 100 ug, 500 ug
Application: WB

Description

Description: Interleukin (IL)-38, a newly discovered IL-1 family cytokine, is expressed in several tissues and secreted by various cells. IL-38 has recently been reported to exert an anti-inflammatory function by binding to several receptors, including interleukin-36 receptor (IL-36R), interleukin-1 receptor accessory protein-like 1 (IL-1RAPL1), and interleukin-1 receptor 1 (IL-1R1) to block binding with other pro-inflammatory cytokines and inhibit subsequent signaling pathways; thereby regulating the differentiation and function of T cells, peripheral blood mononuclear cells, macrophages, and dendritic cells.

Additional Text

Protein Tag

HIS Tag

Accession Number

AAK68048.1

Short Description

Recombinant Human IL-1F10/IL-38 Protein is expressed from Yeast with His tag at the C-terminus.It contains Met1-Trp152.

Storage Note

-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Endotoxin

Less than 1 EU per µg by the LAL method.

Price
£189.00


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