Human Integrin alpha X beta 2 (ITGAX&ITGB2) Heterodimer Protein (ITG-HM1XB)
Catalogue Number: ITG-HM1XB-KAT
ITG-HM1XB Image
ITG-HM1XB Image
ITG-HM1XB Image
ITG-HM1XB Image
The purity of Human ITGAX&ITGB2 is greater than 95% as determined by SEC-HPLC.
ITG-HM1XB Image
Human ITGAX&ITGB2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
ITG-HM1XB Image
Immobilized Human ITGAX&ITGB2, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-ITGB2 Antibody, hFc Tag with the EC50 of 21.4ng/ml determined by ELISA (QC Test).
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 125.50 kDa (ITGAX) and 79.50 kDa (ITGB2). Due to glycosylation, the protein migrates to 130-135 kDa (ITGAX) and 85-95 kDa (ITGB2) based on Bis-Tris PAGE result. |
| Physical state: | Lyophilized |
| Type: | Intergrins |
| Alias: | αXβ2; CD11C; SLEB6; CD18; ITGAX&ITGB2; ITGA; ITGB2 |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA, WB |
Description
Description: The integrin alpha X beta 2 (CD11c/CD18, p150,95) binds ligands through the I domain of the alpha X subunit. Ligands include the complement factor fragment iC3b, a key component in the innate immune defense, which, together with the expression of alpha X beta 2 on dendritic cells and on other leukocytes, suggests a role in the immune response.
Additional Text
Protein Tag
HIS Tag
UniProt ID
P05107-1
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Endotoxin
Less than 1 EU per µg by the LAL method.
Short Description
Recombinant Human Integrin alpha X beta 2(ITGAX&ITGB2) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus of ITGAX.It contains Phe20-Pro1107(ITGAX) acidic tail and Gln23-Asn700(ITGB2) basic tail.
ITG-HM1XB Datasheet
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