Biotinylated Human Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein (ITG-HM4V3B)

Catalogue Number: ITG-HM4V3B-KAT

Manufacturer:	Kactus
Shelf Life:	12 months
Molecular Weight:	The protein has a predicted MW of 114 kDa (ITGAV) & 81.3 kDa (ITGB3). Due to glycosylation, the protein migrates to 100-160 kDa based on Bis-Tris PAGE result.
Physical state:	Lyophilized
Type:	Protein - Conjugated
Alias:	αVβ3; Integrin alpha V beta 3; beta3; alphaV; ITGAV&ITGB3;Integrin alpha V β 3; β3
Host Cell:	HEK293 cells
Shipping Condition:	RT
Unit(s):	100 ug, 500 ug
Application:	ELISA, WB

Overview
Datasheets

Description

Description: ITGAV&ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV&ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV&ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling. ITGAV&ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV&ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling.

Additional Text

Protein Tag

HIS-AviTag™

Uniprot ID

P05106-1, P06756-1

Storage Note

-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Biological Activity

Immobilized Anti-alpha V beta3 Antibody, hFc Tag at 2Oeg/ml (100Oel/well) on the plate. Dose response curve for Biotinylated Human ITGAV&ITGB3, His Tag with the EC50 of 54ng/ml determined by ELISA. See testing image for detail.

Endotoxin

Less than 1 EU per µg by the LAL method.

Short Description

Recombinant Biotinylated Human Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus of ITGAV.It contains Phe31-Val992 (ITGAV) acidic tail and Gly27-Asp718 (ITGB3) basic tail.

ITG-HM4V3B Datasheet

ITG-HM4V3B MSDS

Price

£471.00

-

Quantity
Unit Size

Find out about delivery