J Chain (AP)
Catalogue Number: J1255-AP-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with Alkaline Phosphatase. |
| Type: | Monoclonal Secondary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 3H2560 (Mc19-9) |
| Isotype: | IgG1 |
| Immunogen: | Human J Chain. |
| Application: | ELISA, IP, WB, IHC |
Description
Description: J Chain serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.
Additional Text
Specificity
Recognizes human J chain as tested by ELISA using purified human Ig fragments as the solid phase target antigen. The antibody does not detect J chain in intact IgM in ELISA assays due to steric hindrance. In Western Blot techniques the antibody detects J chain in IgM only in reducing conditions.
Purification
Protein A purified
Antibody Clonality
Monoclonal
J1255-AP Datasheet
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