Anti-CBX5 Monoclonal Antibody

Catalogue Number: K000013M-SLB

Manufacturer:SolarBio
Shelf Life:12 months
Molecular Weight:22kDa
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul, 50 ul
Host name: Mouse
Clone:
Isotype: IgG2b
Immunogen: Recombinant protein of human CBX5
Application: ICC, IF, WB, IHC

Description

Description: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Additional Text

Molecular Weight

22kDa

Gene ID

23468

Gene Name

CBX5

Uniprot ID

P45973

Purification

Affinity Purified

Antibody Clonality

Monoclonal

Storage Note

Store at -20°C. Avoid freeze / thaw cycles. 1 Year