Anti-CHD3(C-term) Monoclonal Antibody

Catalogue Number: K000030M-SLB

Manufacturer:SolarBio
Shelf Life:12 months
Molecular Weight:223/227kDa
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul, 50 ul
Host name: Mouse
Clone:
Isotype: IgG1
Immunogen: Recombinant protein of human CHD3(C-term)
Application: ICC, IF, IP, WB

Description

Description: This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

Additional Text

Gene ID

1107

Gene Name

CHD3

Uniprot ID

Q12873

Purification

Affinity Purified

Antibody Clonality

Monoclonal

Storage Note

Store at -20°C. Avoid freeze / thaw cycles. 1 Year

Molecular Weight

223/227kDa