Anti-ZAP70 Monoclonal Antibody
Catalogue Number: K000126M-SLB
| Manufacturer: | SolarBio |
| Shelf Life: | 12 months |
| Molecular Weight: | 70kDa |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Mouse |
| Clone: | |
| Isotype: | IgG2b |
| Immunogen: | Recombinant protein of human ZAP70 |
| Application: | IP, WB |
Description
Description: This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Additional Text
Molecular Weight
70kDa
Gene ID
7535
Gene Name
ZAP70
Uniprot ID
P43403
Purification
Affinity Purified
Antibody Clonality
Monoclonal
Storage Note
Store at -20°C. Avoid freeze / thaw cycles. 1 Year
SUPPORT
outstanding technical support
PRODUCT
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DELIVERY
we offer free delivery to UK universities and non profit organisations