Anti-XRCC5 Monoclonal Antibody

Catalogue Number: K000136M-SLB

Manufacturer:SolarBio
Shelf Life:12 months
Molecular Weight:83kDa
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul, 50 ul
Host name: Mouse
Clone:
Isotype: IgG1
Immunogen: Recombinant protein of human XRCC5
Application: ICC, IF, IP, ChIP, WB

Description

Description: The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. (provided by RefSeq, Jul 2008).

Additional Text

Molecular Weight

83kDa

Gene Name

XRCC5

Uniprot ID

P13010

Gene ID

7520

Purification

Affinity Purified

Antibody Clonality

Monoclonal

Storage Note

Store at -20°C. Avoid freeze / thaw cycles. 1 Year