Anti-SMARCA4 Monoclonal Antibody

Catalogue Number: K000144M-SLB

Manufacturer:SolarBio
Shelf Life:12 months
Molecular Weight:185kDa
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul, 50 ul
Host name: Mouse
Clone:
Isotype: IgG1
Immunogen: Recombinant protein of human SMARCA4
Application: ICC, IF, IP, WB

Description

Description: The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila.Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes.The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI,which is required for transcriptional activation of genes normally repressed by chromatin.In addition, this protein can bind BRCA1,as well as regulate the expression of the tumorigenic protein CD44.Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2.Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq,May 2012]

Additional Text

Gene Name

SMARCA4

Gene ID

6597

Uniprot ID

P51532

Molecular Weight

185kDa

Purification

Affinity Purified

Antibody Clonality

Monoclonal

Storage Note

Store at -20°C. Avoid freeze / thaw cycles. 1 Year