Anti-EIF2S1 Monoclonal Antibody

Catalogue Number: K000162M-SLB

Manufacturer:SolarBio
Shelf Life:12 months
Molecular Weight:36kda
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul, 50 ul
Host name: Mouse
Clone:
Isotype: IgG2b
Immunogen: Recombinant protein of human EIF2S1
Application: ICC, IF, IP, WB

Description

Description: The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).

Additional Text

Molecular Weight

36kDa

Gene Name

EIF2S1

Gene ID

1965

Uniprot ID

P05198

Purification

Affinity Purified

Antibody Clonality

Monoclonal

Storage Note

Store at -20°C. Avoid freeze / thaw cycles. 1 Year