Anti-LRP5 Polyclonal Antibody

Catalogue Number: K001578P-SLB

Manufacturer:SolarBio
Shelf Life:12 months
Molecular Weight:179kDa
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul, 50 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: A synthetic peptide of human LRP5
Application: IF, WB

Description

Description: This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants.

Additional Text

Gene Name

LRP5

Uniprot ID

O75197

Gene ID

4041

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Molecular Weight

179kDa

Storage Note

Store at -20°C. Avoid freeze/thaw cycles. 1 Year