Anti-POLR2A Polyclonal Antibody

Catalogue Number: K002155P-SLB

Manufacturer:SolarBio
Shelf Life:12 months
Molecular Weight:217kDa
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul, 50 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: A synthetic peptide of human POLR2A
Application: IF, ChIP, WB, IHC

Description

Description: This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.

Additional Text

Gene ID

5430

Gene Name

POLR2A

Uniprot ID

P24928

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Molecular Weight

217kDa

Storage Note

Store at -20°C. Avoid freeze/thaw cycles. 1 Year