Anti-CKAP5 Polyclonal Antibody

Catalogue Number: K005899P-SLB

Manufacturer:SolarBio
Shelf Life:12 months
Molecular Weight:225kDa
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul, 50 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant protein of human CKAP5
Application: IF, IP, WB

Description

Description: This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation; it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified.

Additional Text

Uniprot ID

Q14008

Purification

Affinity Purified

Gene ID

9793

Gene Name

CKAP5

Antibody Clonality

Polyclonal

Molecular Weight

225kDa

Storage Note

Store at -20°C. Avoid freeze/thaw cycles. 1 Year