Anti-Phospho-TP53-S46 Polyclonal Antibody
Catalogue Number: K006218P-SLB
| Manufacturer: | SolarBio |
| Shelf Life: | 12 months |
| Molecular Weight: | 44kda |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding S46 of human TP53 |
| Application: | IP, WB |
Description
Description: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277).
Additional Text
Molecular Weight
44kDa
Gene Name
TP53
Gene ID
7157
Uniprot ID
P04637
Purification
Affinity Purified
Antibody Clonality
Polyclonal
Storage Note
Store at -20°C. Avoid freeze/thaw cycles. 1 Year
SUPPORT
outstanding technical support
PRODUCT
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DELIVERY
we offer free delivery to UK universities and non profit organisations