Anti-TNF alpha Monoclonal Antibody

Catalogue Number: K009343M-SLB

Manufacturer:SolarBio
Shelf Life:12 months
Molecular Weight:17/26kDa
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul, 50 ul
Host name: Mouse
Clone:
Isotype: IgG1
Immunogen: Recombinant protein of human TNF alpha
Application: ELISA, ICC, IF, WB, IHC

Description

Description: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.

Additional Text

Gene Name

TNF

Gene ID

7124

Uniprot ID

P01375

Purification

Affinity Purified

Antibody Clonality

Monoclonal

Molecular Weight

17/26kDa

Storage Note

Store at -20°C. Avoid freeze / thaw cycles. 1 Year