Anti-Pan Cytokeratin Polyclonal Antibody

Catalogue Number: K009347P-SLB

Manufacturer:SolarBio
Shelf Life:12 months
Molecular Weight:42-64kDa
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul, 50 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: A synthetic peptide of rat Pan Cytokeratin
Application: ELISA, FC, ICC, IF, WB, IHC

Description

Description: Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9-K23, and the hair keratins Ha1-Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1-K8, and the hair keratins, Hb1-Hb6.??In the cytoplasm, the keratin filaments conform a complex network which extends from the surface of the nucleus to the cell membrane.?Apart from the relatively static functions provided in terms of supporting the nucleus and providing tensile strength to the cell, the cytokeratin networks undergo rapid phosphate exchanges mediated depolymerization, with important implications in the more dynamic cellular processes such as mitosis and post-mitotic period, cell movement and differentiation.

Additional Text

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Molecular Weight

42-64kDa

Storage Note

Store at -20°C. Avoid freeze / thaw cycles. 1 Year