Anti-SARS spike glycoprotein S1 Polyclonal Antibody

Catalogue Number: K009372P-SLB

Manufacturer:SolarBio
Shelf Life:12 months
Molecular Weight:138kDa
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul, 50 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: A synthetic peptide of human SARS glycoprotein S1
Application: ELISA, ICC, IF, IHC

Description

Description: S1 attaches the virion to the cell membrane by interacting with human ACE2 and CLEC4M/DC-SIGNR, initiating the infection. Binding to the receptor and internalization of the virus into the endosomes of the host cell probably induces conformational changes in the S glycoprotein. Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes.

Additional Text

Uniprot ID

P59594

Purification

Affinity Purified

Molecular Weight

138kDa

Antibody Clonality

Polyclonal

Storage Note

Store at -20°C. Avoid freeze / thaw cycles. 1 Year