Anti-CD3 (FITC) Monoclonal Antibody
Catalogue Number: K009954M-SLB
| Manufacturer: | SolarBio |
| Shelf Life: | 12 months |
| Molecular Weight: | 20kDa |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 25 ug |
| Host name: | Rat |
| Clone: | |
| Isotype: | IgG2b, kappa |
| Immunogen: | γδTCR-positive T-T hybridoma D1 |
| Application: | FC |
Description
Description: CD3 is a multimeric protein associated with the T-cell receptor (TCR) to form a complex involved in antigen recognition and signal transduction (PMID: 15885124). CD3 is composed of CD3γ, δ, ε, and ζ chains (PMID: 1826255). It is expressed by thymocytes in a developmentally regulated manner, T cells, and some NK cells (PMID: 3289580). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657).
Additional Text
Molecular Weight
20kDa
Gene Name
CD3E
Gene ID
12501
Uniprot ID
P22646
Purification
Affinity Purified
Antibody Clonality
Monoclonal
Storage Note
Store at 2-8°C. Avoid light. 1 Year
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations