Anti-IGSF3 Polyclonal Antibody

Catalogue Number: K010023P-SLB

Manufacturer:SolarBio
Shelf Life:12 months
Molecular Weight:133kDa
Physical state:Liquid
Type:Polyclonal Secondary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul, 50 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: A synthetic peptide of human IGSF3
Application: ELISA, ICC, IF, WB, IHC

Description

Description: IGSF3, also known as V8 or EWI-3, is a 1,214 amino acid protein. Widely expressed with predominant expression in kidney, placenta and lung, IGSF3 localizes to the membrane and contains an N-terminal signal peptide, eight immunoglobulin (Ig) domains and a transmembrane segment. IGSF3 exhibits strong sequence and structural similarity to CD101 (32% identity), a leukocyte surface protein with seven Ig domains that is believed to play a role in T-cell activation. Despite the structural similarities between IGSF3 and CD101, IGSF3 is not expressed in peripheral blood lymphocytes and does not appear to participate in an immune function. Based on its subcellular localization and the presence of the eight Ig domains, IGSF3 is hypothesized to function as a surface receptor or as a cell adhesion molecule.

Additional Text

Purification

Affinity Purified

Molecular Weight

133kDa

Gene ID

3321

Uniprot ID

O75054

Gene Name

IGSF3

Antibody Clonality

Polyclonal

Storage Note

Store at -20°C. Avoid freeze / thaw cycles. 1 Year