Anti-CD80(PE) Monoclonal Antibody
Catalogue Number: K010097M-SLB
| Manufacturer: | SolarBio |
| Shelf Life: | 12 months |
| Molecular Weight: | 32kDa |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 25 ug |
| Host name: | Armenian Hamster |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | CHO cell line transfected with mouse B7 (CD80) |
| Application: | FC |
Description
Description: CD80 (also known as B7-1) is a type I membrane protein that is a member of the immunoglobulin superfamily, with an extracellular immunoglobulin constant-like domain and a variable-like domain required for receptor binding. It is expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, monocytes, and macrophages. CD80 is the receptor for the proteins CD28 and CTLA-4 found on the surface of T-cells. It is involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. CD80 also acts as a cellular attachment receptor for adenovirus subgroup B. (PMID: 7545666; 12015893; 16920215)
Additional Text
Molecular Weight
32kDa
Gene Name
CD80
Gene ID
12519
Uniprot ID
Q00609
Purification
Affinity Purified
Antibody Clonality
Monoclonal
Storage Note
Store at 2-8°C. Avoid light. 1 Year
SUPPORT
outstanding technical support
PRODUCT
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DELIVERY
we offer free delivery to UK universities and non profit organisations