Anti-CD11c(APC) Monoclonal Antibody
Catalogue Number: K010129M-SLB
| Manufacturer: | SolarBio |
| Shelf Life: | 12 months |
| Molecular Weight: | 126kDa |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 25 ug |
| Host name: | Armenian Hamster |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Mouse spleen dendritic cells |
| Application: | FC |
Description
Description: Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11c, also known as integrin αX, is a type I transmembrane glycoprotein present on a variety of cells, including monocytes/macrophages, granulocytes, a subset of B cells, NK cells and dendritic cells (PMID: 2897326; 1680915; 1694698; 17389580). As a result of its high level of expression on most dendritic cells, CD11c is typically considered to be a marker of conventional dendritic cells (PMID: 27119555). CD11c forms an α/β heterodimer with CD18 (integrin β2). CD11c/CD18 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis (PMID: 1671533).
Additional Text
Gene Name
ITGAX
Gene ID
16411
Uniprot ID
Q9QXH4
Purification
Affinity Purified
Molecular Weight
126kDa
Antibody Clonality
Monoclonal
Storage Note
Store at 2-8°C. Avoid exposure to light. 1 Year
SUPPORT
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PRODUCT
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DELIVERY
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