Anti-F4/80(FITC) Monoclonal Antibody
Catalogue Number: K010161M-SLB
| Manufacturer: | SolarBio |
| Shelf Life: | 12 months |
| Molecular Weight: | 97kDa |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests |
| Host name: | Rat |
| Clone: | |
| Isotype: | IgG2b |
| Immunogen: | A synthetic peptide of mouse F4/80 |
| Application: | FC |
Description
Description: F4/80 is a 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is expressed on the majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and Peyer's patch), Kuffer cells, Langerhans cells, and bone marrow stromal cells. F4/80 has also been shown on a subset of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for induction of CD8+ T cells-mediated peripheral tolerance.
Additional Text
Gene ID
13733
Uniprot ID
Q61549
Molecular Weight
97kDa
Purification
Affinity Purified
Gene Name
ADGRE1
Antibody Clonality
Monoclonal
Storage Note
Store at 2-8°C. Avoid exposure to light. 1 Year
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