Catalogue Number: K010164M-SLB
| Manufacturer: | SolarBio |
| Shelf Life: | 12 months |
| Molecular Weight: | 38kda |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests, 25 tests |
| Host name: | Mouse |
| Clone: | |
| Isotype: | IgG1, kappa |
| Immunogen: | B-lymphoblastoid cell line ARH 77 |
| Application: | FC |
Description: CD86 (also known as B7.2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response.
38kDa
CD86
942
P42081
Monoclonal
Store at 2-8°C. Avoid exposure to light. 1 Year