Anti-CD83 Monoclonal Antibody

Catalogue Number: K010167M-SLB

Manufacturer:SolarBio
Shelf Life:12 months
Molecular Weight:23kDa
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug, 25 ug
Host name: Mouse
Clone:
Isotype: IgG1, kappa
Immunogen: Human CD83-transfected Cos cells
Application: FC

Description

Description: The CD83 antigen is a 186 amino acid single chain glycoprotein. This molecule is a member of the immunoglobulin superfamily and is composed of an extracellular V type immunoglobulin-like single domain, a transmembrane region, and a short, 40 amino acid cytoplasmic tail. CD83 antigen undergoes extensive post translational glycosylation, as the determined Mr is twice the predicted size of the core protein. However, CD83+ cells have a unique cell surface immunophenotype that does not correlate with that of T cells, B cells, NK cells, or cells of the myelomonocytic lineage. CD83+ cells coexpress the highest levels of MHC class II molecules, when compared with other leucocyte lineages. They also coexpress T cell markers (CD2, CD5), B cell markers (CD40, CD78), myeloid cell markers (CD13, CD33, CD36) and cytokine receptors, as well as other cell surface molecules.

Additional Text

Molecular Weight

23kDa

Gene ID

9308

Gene Name

CD83

Uniprot ID

Q01151

Purification

Affinity Purified

Antibody Clonality

Monoclonal

Storage Note

Store at 2-8°C. Avoid exposure to light. 1 Year