Anti-HLA-DRA(FITC) Monoclonal Antibody
Catalogue Number: K010170M-SLB
| Manufacturer: | SolarBio |
| Shelf Life: | 12 months |
| Molecular Weight: | 29kDa |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests, 25 tests |
| Host name: | Mouse |
| Clone: | |
| Isotype: | IgG2a, kappa |
| Immunogen: | Recombinant protein of Human HLA-DR |
| Application: | FC |
Description
Description: HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq]
Additional Text
Molecular Weight
29kDa
Gene Name
HLA-DRA
Gene ID
3122
Uniprot ID
P01903
Purification
Protein A purified
Antibody Clonality
Monoclonal
Storage Note
Store at 2-8°C. Avoid exposure to light. 1 Year
SUPPORT
outstanding technical support
PRODUCT
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DELIVERY
we offer free delivery to UK universities and non profit organisations