Anti-CD3(PE) Monoclonal Antibody

Catalogue Number: K010183M-SLB

Manufacturer:SolarBio
Shelf Life:12 months
Molecular Weight:20kDa
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 tests, 25 tests
Host name: Mouse
Clone:
Isotype: IgG2a, kappa
Immunogen:
Application: FC

Description

Description: CD3 is a multimeric protein associated with the T-cell receptor (TCR) to form a complex involved in antigen recognition and signal transduction (PMID: 15885124). CD3 is composed of CD3γ, δ, ε, and ζ chains (PMID: 1826255). It is expressed by thymocytes in a developmentally regulated manner, T cells, and some NK cells (PMID: 3289580). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657).

Additional Text

Molecular Weight

20kDa

Gene Name

CD3E

Gene ID

916

Uniprot ID

P07766

Purification

Affinity Purified

Antibody Clonality

Monoclonal

Storage Note

Store at 2-8°C. Avoid exposure to light. 1 Year

Price
£175.00


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