Anti-NPHS2 Polyclonal Antibody

Catalogue Number: K010442P-SLB

Manufacturer:SolarBio
Shelf Life:12 months
Molecular Weight:42kda
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul, 50 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: A synthetic peptide of human NPHS2
Application: ELISA, WB, IHC

Description

Description: This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined.

Additional Text

Molecular Weight

42kDa

Gene Name

NPHS2

Uniprot ID

Q9NP85

Gene ID

7827

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Storage Note

Store at -20°C. Avoid freeze / thaw cycles. 1 Year