Anti-NMDAR2B/GRIN2B Polyclonal Antibody
Catalogue Number: K010549P-SLB
| Manufacturer: | SolarBio |
| Shelf Life: | 12 months |
| Molecular Weight: | 166kDa |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Recombinant protein of human NMDAR2B/GRIN2B |
| Application: | ELISA, FC, IF, IP, WB, IHC |
Description
Description: GRIN2B (also known as GluN2B or NMDAR2B) is a member of the N-methyl-D-aspartate (NMDA) receptor family within the ionotropic glutamate receptor superfamily. NMDA receptors are widely expressed in the central nervous system and play a major role in excitatory synaptic transmission and plasticity (PMID: 23223336). NMDA receptors large multi-subunit complexes arranged into heteromeric assemblies composed of four homologous subunits within a repertoire of over 10 different subunits: eight GluN1 isoforms, four GluN2 subunits (A-D) and two GluN3 subunits (A and B) (PMID: 21395862). Naturally occurring mutations within GRIN2B gene are associated with neurodevelopmental disorders including autism spectrum disorder, attention deficit hyperactivity disorder, epilepsy, and schizophrenia.
Additional Text
Gene Name
GRIN2B
Gene ID
2904
Uniprot ID
Q13224
Purification
Affinity Purified
Molecular Weight
166kDa
Antibody Clonality
Polyclonal
Storage Note
Store at -20°C. Avoid freeze / thaw cycles. 1 Year
SUPPORT
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PRODUCT
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DELIVERY
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