Anti-CD3(APC) Monoclonal Antibody

Catalogue Number: K010561M-SLB

Manufacturer:SolarBio
Shelf Life:12 months
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 tests, 25 tests
Host name: Mouse
Clone:
Isotype: IgG1, kappa
Immunogen:
Application: FC

Description

Description: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].

Additional Text

Gene Name

CD3E

Gene ID

12501

Uniprot ID

P22646

Antibody Clonality

Monoclonal

Storage Note

Store at 4°C in dark.Do not freeze. 1 Year

Price
£493.00


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