Anti-CD115(APC) Monoclonal Antibody
Catalogue Number: K010640M-SLB
| Manufacturer: | SolarBio |
| Shelf Life: | 12 months |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests, 25 tests |
| Host name: | Rat |
| Clone: | |
| Isotype: | IgG1, kappa |
| Immunogen: | |
| Application: | FC |
Description
Description: This protein tyrosine kinase transmembrane receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy.
Additional Text
Uniprot ID
P07333
Gene Name
CSF1R
Gene ID
1436
Antibody Clonality
Monoclonal
Storage Note
Store at 4°C in dark.Do not freeze. 1 Year
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