Anti-CD152 Monoclonal Antibody

Catalogue Number: K011325M-SLB

Manufacturer:SolarBio
Shelf Life:12 months
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 1 mg, 100 ug
Host name: Human
Clone:
Isotype: IgG1, kappa
Immunogen:
Application: FC

Description

Description: This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]

Additional Text

Gene ID

12477

Gene Name

CTLA4

Uniprot ID

P09793

Antibody Clonality

Monoclonal

Storage Note

Store at 4°C in dark.Do not freeze. 1 Year