Anti-IGHG1 Polyclonal Antibody

Catalogue Number: K108386P-SLB

Manufacturer:SolarBio
Shelf Life:12 months
Molecular Weight:36kda
Physical state:Liquid
Type:Polyclonal Secondary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul, 20 ul, 50 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant protein of human IGHG1
Application: IHC

Description

Description: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.

Additional Text

Molecular Weight

36kDa

Gene ID

3500

Gene Name

IGHG1

Uniprot ID

P01857

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Storage Note

Store at -20°C. Avoid freeze/thaw cycles. 1 Year

Price
£223.00


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