Anti-GAPDH Polyclonal Antibody

Catalogue Number: K110496P-SLB

Manufacturer:SolarBio
Shelf Life:12 months
Molecular Weight:32/36kDa
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul, 50 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant protein of human GAPDH
Application: IF, IP, WB, IHC

Description

Description: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. It catalyzes an important energy-yielding step in carbohydrate metabolism, thereversible oxidative phosphorylation of glyceraldehyde-3-phosphatein the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). Recent evidence suggests that it also is involved in a number of cellular processes such as membrane fusion, phosphotransferase activity, DNA replication and repair, and nuclear RNA export (1). GAPDH has also been implicated in playing a role in different pathologies such as cancer progression, apoptosis, and neuronal diseases such as Alzheimer's and Huntington's disease (2). GAPDH is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots.

Additional Text

Gene Name

GAPDH

Gene ID

2597

Uniprot ID

P04406

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Storage Note

Store at -20°C. Avoid freeze/thaw cycles. 1 Year

Molecular Weight

32/36kDa