Kinesin, Heavy Chain (MaxLight 550)

Catalogue Number: K1780-01-ML550-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™550.
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	conventional kinesin heavy chain\|epididymis secretory protein Li 61\|HEL-S-61\|kinesin 1 (110-120kD)\|kinesin heavy chain\|kinesin-1 heavy chain\|KINH\|KNS\|KNS1\|ubiquitous kinesin heavy chain\|UKHC
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	2Q81 (H2)
Isotype:	IgG2b
Immunogen:	Bovine brain kinesin
Application:	ICC, IP, WB, RIA, IHC, FLISA

Overview
Datasheets

Description

Description: MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. Kinesin belongs to the group of motor proteins known to convert chemical energy released from ATP into mechanical energy. Conventional kinesin, member of the kinesin superfamily comprising more than 100 proteins, is involved in the anterograde vesicle transport inneuronal cells. Kinesin purified from mammalian brain homogenates is a heterotetramer consisting of two heavy (120-130kD) and two light chains (60-70kD), resulting in a molecular mass about 400kD. Each heavy chain contains an N-terminal globular motordomain with both a microtubule-binding site and an ATPase active center, stalk region responsible for heavy chain dimerization and finally C-terminal globular tail domain, which is implicated in cargo binding. Light chains may have a regulatory function.

Additional Text

Gene Name

KIF5B

Uniprot ID

P33176

Specificity

Recognizes bovine heavy chain of kinesin near the N-terminus. Species Crossreactivity: All mammals, chicken, squid, sea urchins and clams.

Accession Number

NP_004512

Gene ID

3799

Purification

Protein A purified

Antibody Clonality

Monoclonal

K1780-01-ML550 Datasheet

Price

£1,031.00

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