Kinesin, Heavy Chain (MaxLight 550)

Catalogue Number: K1780-02-ML550-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™550.
Type:	Monoclonal Primary Antibody - Conjugated
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	2Q80 (H1)
Isotype:	IgG1
Immunogen:	Bovine brain kinesin
Application:	ICC, IP, WB, RIA, IHC, FLISA

Overview
Datasheets

Description

Description: MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. Kinesin belongs to the group of motor proteins known to convert chemical energy released from ATP into mechanical energy. Conventional kinesin, member of the kinesin superfamily comprising more than 100 proteins, is involved in the anterograde vesicle transport inneuronal cells. Kinesin purified from mammalian brain homogenates is a heterotetramer consisting of two heavy (120-130kD) and two light chains (60-70kD), resulting in a molecular mass about 400kD. Each heavy chain contains an N-terminal globular motordomain with both a microtubule-binding site and an ATPase active center, stalk region responsible for heavy chain dimerization and finally C-terminal globular tail domain, which is implicated in cargo binding. Light chains may have a regulatory function.

Additional Text

Specificity

Recognizes the heavy chain of bovine kinesin near the N-terminus. Species Crossreactivity: All mammals, other vertebrates not tested. Does not react with invertebrates.

Purification

Purified

Antibody Clonality

Monoclonal

Accession Number

NM_004521.1

Uniprot ID

A0A3Q1MXL6

K1780-02-ML550 Datasheet

Price

£1,031.00

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