Kinesin, Heavy Chain (MaxLight 650)
Catalogue Number: K1780-02-ML650-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 2Q80 (H1) |
| Isotype: | IgG1 |
| Immunogen: | Bovine brain kinesin |
| Application: | ICC, IP, WB, RIA, IHC, FLISA |
Description
Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. Kinesin belongs to the group of motor proteins known to convert chemical energy released from ATP into mechanical energy. Conventional kinesin, member of the kinesin superfamily comprising more than 100 proteins, is involved in the anterograde vesicle transport inneuronal cells. Kinesin purified from mammalian brain homogenates is a heterotetramer consisting of two heavy (120-130kD) and two light chains (60-70kD), resulting in a molecular mass about 400kD. Each heavy chain contains an N-terminal globular motordomain with both a microtubule-binding site and an ATPase active center, stalk region responsible for heavy chain dimerization and finally C-terminal globular tail domain, which is implicated in cargo binding. Light chains may have a regulatory function.
Additional Text
Specificity
Recognizes the heavy chain of bovine kinesin near the N-terminus. Species Crossreactivity: All mammals, other vertebrates not tested. Does not react with invertebrates.
Purification
Purified
Antibody Clonality
Monoclonal
Accession Number
NM_004521.1
Uniprot ID
A0A3Q1MXL6
K1780-02-ML650 Datasheet
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