Anti-OsGSK2 Polyclonal Antibody
Catalogue Number: K800017P-SLB
| Manufacturer: | SolarBio |
| Shelf Life: | 12 months |
| Molecular Weight: | 46 kDa |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH-conjugated synthetic peptide of GSK2 derived from Oryza sativa LOC_Os05g11730 |
| Application: | WB |
Description
Description: Serine-threonine kinase that acts as a negative regulator of brassinosteroid (BR) signaling (PubMed:22685166, PubMed:27332964, PubMed:30920691). Phosphorylates DLT and BZR1, two positive regulators that mediates several BR responses. Phosphorylation of DLT and BZR1 inhibits their activities in BR signaling (PubMed:22685166). Phosphorylates OFP8, a positive regulator of BR responses. Phosphorylated OFP8 shuttles from the nucleus to the cytoplasm where it is degraded by the proteasome (PubMed:27332964). Phosphorylates the E3 ubiquitin-protein ligase PUB24, a negative regulator of BR signaling, which targets BZR1 and promotes its degradation via the 26S proteasome (PubMed:30920691). Phosphorylation of PUB24 increases its stability (PubMed:30920691). Phosphorylates the AP2-ERF transcription factor SMOS1, a positive regulator of BR signaling, which cooperatively functions in a transactivating complex with BZR1 to enhance the transcription of BR biosynthetic genes (PubMed:30920691). Phosphorylation of SMOS1 leads to its degradation by an unknown mechanism (PubMed:30920691).
Additional Text
Molecular Weight
46 kDa
Antibody Clonality
Polyclonal
Gene ID
4338079
Gene Name
LOC4338079
Uniprot ID
Q60EZ2
Storage Note
Store at -20°C. Avoid freeze/thaw cycles. 1 Year
SUPPORT
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DELIVERY
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