Anti-COP1 Polyclonal Antibody for Plant
Catalogue Number: K900056P-SLB
| Manufacturer: | SolarBio |
| Shelf Life: | 12 months |
| Molecular Weight: | 76kDa |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of Arabidopsis thaliana COP1 |
| Application: | ELISA, WB |
Description
Description: E3 ubiquitin-protein ligase that acts as a repressor of photomorphogenesis and as an activator of etiolation in darkness. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Represses photomorphogenesis in darkness by mediating ubiquitination and subsequent proteasomal degradation of light-induced transcription factors such as HY5, HYH and LAF1. Down-regulates MYB21, probably via ubiquitination process. Light stimuli abrogate the repression of photomorphogenesis, possibly due to its localization to the cytoplasm. Could play a role in switching between skotomorphogenetic and photomorphogenetic pathways. Mediates the ubiquitination-dependent degradation of HY5 in the darkness during seedling development (e.g. hypocotyl growth) (PubMed:26474641).
Additional Text
Molecular Weight
76kDa
Gene Name
COP1
Antibody Clonality
Polyclonal
Gene ID
817857
Uniprot ID
P43254
Storage Note
Store at -20°C. Avoid freeze / thaw cycles. 1 Year
SUPPORT
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PRODUCT
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DELIVERY
we offer free delivery to UK universities and non profit organisations