Caspase-1 Assay Kit (Colorimetric)
Catalogue Number: KTA3020-ABK
| Manufacturer: | Abbkine |
| Shelf Life: | 12 months |
| Type: | Enzyme Assays |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 T, 20 T, 50 T |
Description
Description: Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Mammalian caspases can be subdivided into three functional groups: initiator caspases (Caspase 2, 8, 9 and 10), executioner caspases (Caspase-3, 6 and 7), and inflammatory caspases (Caspase 1, 4, 5, 11 and 12). Caspase-1 (ICE, interleukin-1β-converting enzyme) is the mammalian caspase responsible for the proteolytic conversion of the proforms of two inflammatory cytokines, interleukin-1β and IL-18 into active cytokines, initiating a proinflammatory response. It also cleaves Gasdermin D into its active form, which leads to pyroptosis.
Additional Text
Short Description
Caspase-1 Assay Kit (Colorimetric) provides a simple and convenient method for detecting the activity of caspase-1.
KTA3020 Datasheet
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