Caspase-8 Assay Kit (Colorimetric)

Catalogue Number: KTA3025-ABK

Manufacturer:Abbkine
Type:Enzyme Assays
Shipping Condition:Blue Ice
Unit(s): 100 T, 20 T, 50 T

Description

Description: Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Mammalian caspases can be subdivided into three functional groups: initiator caspases (Caspase 2, 8, 9 and 10), executioner caspases (Caspase-3, 6 and 7), and inflammatory caspases (Caspase 1, 4, 5, 11 and 12). Caspase-8 (also known as FLICE, MASH, Mch5) is a member of the caspase-family of cysteine proteases. During apoptosis procaspase-8 is processed at aspartate residues by self-proteolysis and/or cleavage by another caspase. The processed active form of caspase-8 consists of large and small subunits which associate to form the active enzyme. Active caspase-8 has been shown to activate caspase-3 leading to degradation of a variety of cellular target proteins during apoptosis.

Additional Text

Short Description

Caspase-8 Assay Kit (Colorimetric) provides a simple and convenient method for detecting the activity of caspase-8.

Price
267.00


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