L1 Cell Adhesion Molecule (L1CAM) (MaxLight 550)
Catalogue Number: L0010-01-ML550-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with MaxLight™550. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 6A103 |
| Isotype: | IgG1, kappa |
| Immunogen: | 3T3 fibroblasts transfected with the human L1 protein |
| Application: | ICC, IF, IP, FLISA |
Description
Description: The L1 adhesion molecule is a 200-220kD membrane glycoprotein of the immunoglobulin superfamily. Initially studied in the nervous system, L1 is involved in important processes such as neuron-neuron adhesion and migration, axonal outgrowth and fasciculation, myelination, and synaptic plasticity. Mutations in the L1 gene product have been shown to cause abnormal brain development. Outside the nervous system, L1 is expressed in hematopoietic and certain epithelial cells in humans. L1 is also active in the mitogen-activated protein kinase (MAPK) signaling cascade.
Additional Text
Specificity
Recognizes human L1 protein. Species Sequence Homology: 88% homology with mouse and rat L1.
Purification
Protein A purified
Antibody Clonality
Monoclonal
L0010-01-ML550 Datasheet
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