Lck, p56 (Lymphocyte-specific Tyrosine Kinase) (BSA & Azide Free) (MaxLight 650)

Catalogue Number: L1565-01X-ML650-USB

Manufacturer:United States Biological
Preservative:BSA & Azide Free
Physical state:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650.
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 0.N.385
Isotype: IgG2b, kappa
Immunogen: Recombinant protein corresponding to aa1-225 of mouse p56lck protein. Cellular Localization: Cell membrane
Application: ELISA, IP, WB

Description

Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000 p56lck is a membrane-associated non-receptor protein tyrosine kinase from the Src family of kinases. The phosphorylation status and the activity of p56lck is regulated by the CD45 tyrosine protein phosphatase. p56lck plays a critical role in T cell development and activation. p56lck gene is localized to a site in the genome which undergoes frequent chromosomal abnormalities in lymphomas and neuroblastomas.

Additional Text

Specificity

Recognizes Lck at 56kD. Species Crossreactivity: Human, mouse and rat.

Purification

Protein A purified

Antibody Clonality

Monoclonal