IHC-plus™ TS / Thymidylate Synthase Antibody

Catalogue Number: LS-B9494-LSP

Manufacturer:LifeSpan BioSciences Inc.
Preservative:0.01% Sodium azide
Physical state:Lyophilized
Type:Polyclonal Primary Antibody - Unconjugated
Alias:TYMS, HST422, Thymidylate synthetase, TMS, TS, Thymidylate synthase, Tsase
Shipping Condition:RT
Unit(s): 0.5 ml
Host name: Sheep
Clone:
Isotype:
Immunogen: This whole sheep serum was prepared by repeated immunizations with recombinant human Thymidylate Synthase (36 kDa) produced in E.coli.
Application: ELISA, IHC-P, WB, IHC

Additional Text

Gene Name

TYMS

Antigen Type

Recombinant Protein

Gene ID

7298

Short Description

Thymidylate Synthase antibody LS-B9494 is an unconjugated sheep polyclonal antibody to Thymidylate Synthase (TS) from human. It is reactive with human, mouse and rat. Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues.

Storage Note

Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.

Antibody Clonality

Polyclonal

Application Notes

This antiserum against Human Thymidylate Synthase (hTS) has been tested for use in ELISA, immunohistochemistry with FFPE human tissues, and immunoblotting. The antibody recognizes the expected additional band corresponding to the ternary complex of hTS-dFUMP-reduced folate in HeLa cells treated with the TS inhibitor 5-FUdR. This event occurs in most human breast, colorectal, gastric, head and neck carcinomas. The antibody recognizes the 36000 MW hTS.